In people struggling with weight, this signal is often weak or delayed, leading to overeating and energy imbalance
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However, the VPA model was specifically selected for its ability to: (1) mimic the gut microbiota dysbiosis observed in ASD patients [45], which genetic models often fail to reproduce [44]
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Individual trials have proven that they can effectively lead to good glycemic control and clinically significant weight loss in patients with T2D (Sorli et al., 2017
